Introduction: Scrub typhus is a re-emerging threat worldwide and meningitis due to it is being increasingly recognised. There are few studies on paediatric patients with scrub typhus meningitis.
Objective: To describe the epidemiological, clinical and laboratory profile of children admitted with scrub typhus meningitis to a hospital in eastern India along with treatment outcome.
Method: This is a retrospective analysis of the hospital records from September 2015 to January 2017 of all children between 1 month to 12 years of age admitted to the Institute of Child Health, Kolkata, India, with fever, neck rigidity and evidence of both meningitis and scrub typhus. The epidemiological features, clinical signs and symptoms, laboratory findings and treatment outcomes of the children were noted. Chi‑square test was used for comparing categorical variables and the student’s unpaired t‑test for comparing the continuous variables. A p-value of less than 0.05 was considered statistically significant.
Results: There were five children with scrub typhus, with a CSF picture of meningitis during the study period. Mean duration of fever before presentation was 11.6 ± 1.8 days. The male: female ratio was 4:1 and the urban: rural ratio 1:4. The mean age was 78 ± 37.5 months. Vomiting, headache, altered sensorium and seizures were the common symptoms. Signs of meningeal irritation, pallor and lymphadenopathy were the common findings on physical examination.
Conclusion: Meningitis is an uncommon complication of scrub typhus in children, only 5 cases being recorded from September 2015 to January 2017 at the Institute of Child Health, Kolkata, India.
Sri Lanka Journal of Child Health, 2018; 47(1): 3-7