Original Articles
Burden associated with childhood bloodstream infection in a resource-constrained setting
Authors:
Folake Moriliat Afolayan ,
University of Ilorin, Ilorin, NG
About Folake
Department of Paediatrics, Faculty of Clinical Sciences
Mohammed Baba Abdulkadir,
Department of Paediatrics, Faculty of Clinical Sciences, University of Ilorin, Ilorin and, NG
About Mohammed
Department of Paediatrics, Faculty of Clinical Sciences
Department of Paediatrics, University of Ilorin Teaching Hospital, Ilorin
Bashirat Ayobola Olanipekun,
University of Ilorin, Ilorin, NG
About Bashirat
Department of Medical Microbiology & Parasitology, Faculty of Basic Clinical Sciences
Adedeji Nurudeen Lawal,
University of Ilorin, Ilorin, NG
About Adedeji
Department of Medical Microbiology & Parasitology, Faculty of Basic Clinical Sciences
Solomon Olubodunrin Ariyib,
University of Ilorin, Ilorin, NG
About Solomon
Department of Paediatrics, Faculty of Clinical Sciences
Olayinka Rasheed Ibrahim,
University of Ilorin Teaching Hospital, Ilorin, NG
About Olayinka
Department of Paediatrics
Harifarta Claphton Difirwiti,
University of Ilorin Teaching Hospital, Ilorin, NG
About Harifarta
Department of Paediatrics
Olugbenga Ayodeji Mokuolu
University of Ilorin, Ilorin, NG
About Olugbenga
Department of Paediatrics, Faculty of Clinical Sciences
Department of Paediatrics, University of Ilorin Teaching Hospital, Ilorin
Abstract
Background: In children, bloodstream infection (BSI) causes significant morbidity and mortality. Most studies in Nigeria focused on the aetiology of childhood BSI with little or no appraisal of burden.
Objectives: To determine the direct cost of childhood BSI, length of hospital stay, and deaths in a tertiary health facility in northcentral Nigeria.
Method: This prospective observational study was conducted in a tertiary hospital in Nigeria. We recruited children aged 0-14 years with the diagnosis of sepsis. Blood samples were collected and processed following standard microbiological techniques. The culture was performed using BacT/Alert machine. The direct costs of caregivers were obtained daily using receipts of all rendered services till outcome (discharged/death). This study's length of stay (LOS) was defined as the number of days the children stayed after admission prior to discharge/death.
Results: Of the 179 blood samples obtained, 91 (50.8%) had bacterial BSI. Gram-positive organisms were the commonest isolated pathogens (70.3%). The mean length of hospitalisation was significantly higher among children with BSI than those without BSI (10.24 ± 8.88 vs. 7.640 ± 5.825 days, p=0.034). Similarly, the mean cost was higher among those with BSI than those without BSI ($89.70±4.91 vs. $66.13±3.98, p <0.001). However, the mortality rate was comparable between those with BSI and without BSI (13.2% vs. 7.9% p=0.361).
Conclusions: This study showed that childhood BSI was associated with an increased direct cost, extended hospitalisation, and relatively high mortality.
Sri Lanka Journal of Child Health, 2023; 52(1): 75-80
How to Cite:
Afolayan, F.M., Abdulkadir, M.B., Olanipekun, B.A., Lawal, A.N., Ariyib, S.O., Ibrahim, O.R., Difirwiti, H.C. and Mokuolu, O.A., 2023. Burden associated with childhood bloodstream infection in a resource-constrained setting. Sri Lanka Journal of Child Health, 52(1), pp.75–80. DOI: http://doi.org/10.4038/sljch.v52i1.10477
Published on
05 Mar 2023.
Peer Reviewed
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