Original Articles
Retrospective comparative study on maternal, fetal, and neonatal outcomes of symptomatic dengue infection: A study in Teaching Hospital, Peradeniya, Sri Lanka
Authors:
Chamara Dalugama ,
University of Peradeniya, LK
About Chamara
Senior Lecturer, University of Peradeniya
Arjuna Medagama,
University of Peradeniya, LK
About Arjuna
Professor, University of Peradeniya
Aruna Shantha Wickramasinghe,
Teaching Hospital, Peradeniya, LK
About Aruna
Registrar in Medicine, Teaching Hospital, Peradeniya
Sajith Priyankara,
University of Peradeniya, LK
About Sajith
Assistant Lecturer, University of Peradeniya
Gayan Bowatte
University of Peradeniya, LK
About Gayan
Senior Lecturer, University of Peradeniya
Abstract
Introduction: Dengue fever is one of the most important mosquito-borne infections and is considered a major health problem in Sri Lanka. The impact of dengue fever on pregnancy is not very well studied owning to small study cohorts and methodical bias.
Objectives: This is a retrospective comparative study to assess the maternal, fetal, and neonatal outcomes in symptomatic dengue infection in pregnancy
Method: The maternal, neonatal, and fetal outcomes of a cohort of pregnant patients with serologically confirmed dengue fever (n=24) were compared with an age-matched group of healthy pregnant mothers without symptomatic dengue illness (n=72).
Results: There were no statistically significant differences in birth weight (p=0.229), prematurity (p=1.000), peripartum complications (p=0.439) and mode of delivery (p=0.246). Neonates born to mothers with dengue infection needed more premature baby unit (PBU) admissions (p<0.01), and a longer hospital stay (p<0.01). Two maternal deaths were due to multi-organ failure with dengue haemorrhagic fever and one symptomatic case of mother-to-child transmission of dengue infection was noted in the study
Conclusions: In this study there were no statistically significant differences in the fetal or neonatal outcomes between the dengue-exposed and un-exposed groups of pregnant mothers. However, 2 maternal deaths were reported in the exposed group of 24 compared to none in the non-exposed group of 72 which is statistically significant (p<0.001).
Sri Lanka Journal of Child Health, 2023; 52(1): 39-44
How to Cite:
Dalugama, C., Medagama, A., Wickramasinghe, A.S., Priyankara, S. and Bowatte, G., 2023. Retrospective comparative study on maternal, fetal, and neonatal outcomes of symptomatic dengue infection: A study in Teaching Hospital, Peradeniya, Sri Lanka. Sri Lanka Journal of Child Health, 52(1), pp.39–44. DOI: http://doi.org/10.4038/sljch.v52i1.10472
Published on
05 Mar 2023.
Peer Reviewed
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