Start Submission Become a Reviewer

Reading: Risk factors associated with juvenile idiopathic arthritis: A study from Eastern India

Download

A- A+
Alt. Display

Original Articles

Risk factors associated with juvenile idiopathic arthritis: A study from Eastern India

Authors:

Gautam Guha,

NRS Medical College, Kolkata, IN
X close

Tapabroto Chatterjee,

Vivekanda Institute of Medical Science, Kolkata, IN
About Tapabroto

X close

Gorky Guha,

St. Xaviers College, Kolkata, IN
About Gorky

X close

Mita Pain,

LBC Kolkata, IN
About Mita

X close

Samar Ranjan Pal,

Vivekanda Institute of Medical Science, Kolkata, IN
About Samar

X close

Suparna Guha

Vivekanda Institute of Medical Science, Kolkata, IN
About Suparna

X close

Abstract

Introduction: There are limited studies which suggest that environmental risk factors or early life exposures, like low birth weight, lack of breast feeding, passive smoking, recurrent childhood infections may have a role in the aetio-pathogenesis of paediatric autoimmune diseases like juvenile idiopathic arthritis (JIA).


Objectives: To study the association of environmental and early risk factors with the development of JIA in a tertiary care hospital in Eastern India.


Method: This case control study was conducted in the Paediatric Rheumatology Clinic of Vivekananda Institute of Medical Sciences (VIMS), India, over a period of 1 year. Enrolled JIA cases, who consented to be a part of the study, were asked to identify at least 2 to 3 healthy playmates of similar age and sex as controls. A 2-page structured oral questionnaire pertaining to environmental and early life risk factors was prepared and patients/controls or their caregivers were asked to answer these.


Results: Birth weight, gestational age, mode of delivery, breast feeding, passive smoking and infections in infancy were not significantly associated with the development of JIA. There was a significant association with sun exposure (p <0.05), non-vegetarian diet (p <0.05) and use of mosquito repellent (p<0.05)


Conclusions: Among the various risk factors assessed we found that in our study there was a significant association of sun exposure (p <0.05), non-vegetarian diet (p<0.05) and use of mosquito repellents (p <0.05) with the development of JIA.


Sri Lanka Journal of Child Health, 2022; 51(4): 535-541

How to Cite: Guha, G., Chatterjee, T., Guha, G., Pain, M., Pal, S.R. and Guha, S., 2022. Risk factors associated with juvenile idiopathic arthritis: A study from Eastern India. Sri Lanka Journal of Child Health, 51(4), pp.535–541. DOI: http://doi.org/10.4038/sljch.v51i4.10366
Published on 05 Dec 2022.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus