Start Submission Become a Reviewer

Reading: Serum vitamin D, zinc, iron and copper levels in children with newly diagnosed coeliac disease

Download

A- A+
Alt. Display

Original Articles

Serum vitamin D, zinc, iron and copper levels in children with newly diagnosed coeliac disease

Authors:

Priyanka Karnani,

Dr S.N. Medical College and attached group of Hospitals, Jodhpur, Rajasthan, IN
About Priyanka
Department of Paediatrics
X close

Raghunath Barupa,

Dr S.N. Medical College and attached group of Hospitals, Jodhpur, Rajasthan, IN
About Raghunath
Department of Paediatrics
X close

S K Vishnoi,

Dr S.N. Medical College and attached group of Hospitals, Jodhpur, Rajasthan, IN
About S K
Department of Paediatrics
X close

Sandeep Choudhary,

Dr S.N. Medical College and attached group of Hospitals, Jodhpur, Rajasthan
About Sandeep
Department of Paediatrics
X close

Rakesh Jora

Dr S.N. Medical College and attached group of Hospitals, Jodhpur, Rajasthan, IN
About Rakesh
Department of Paediatrics
X close

Abstract

Objectives: To assess the occurrence of serum vitamin D, zinc, iron and copper deficiency in children with newly diagnosed coeliac disease (CD) as compared to healthy controls at a tertiary care centre in Western Rajasthan, India


Method: A case control study was conducted in the Gastroenterology Clinic, Department of Paediatrics, Dr S. N. Medical College, Jodhpur, India for a period of one year. Sixty consecutive newly diagnosed CD patients between 2-18 years of age, confirmed via serology and duodenal biopsy, who fulfilled the study criteria, were enrolled as cases in the study. Representative samples of 30 age-and-sex matched healthy subjects were taken as controls. Serum levels of vitamin D, zinc, iron and copper were assessed at diagnosis in cases and controls.


Results: Mean age of the cases in the study was 6.19 ± 3.42 years. Serum vitamin D, zinc, iron and copper deficiency were seen in 55%, 40%, 58.3% and 11.7% cases respectively. The median (IQR) of serum vitamin D (p=0.002), zinc (p<0.001) and iron (p=0.003) were significantly lower in cases as compared to controls. A statistically significant correlation was seen between serum tissue transglutaminase (TTG) and mean serum vitamin D levels of cases in the study group (p<0.05) and between vitamin D levels and short stature (p <0.001).


Conclusions: Vitamin D, zinc and iron deficiencies were more frequently observed in children with newly diagnosed CD as compared to healthy controls.


Sri Lanka Journal of Child Health, 2022; 51(4): 519-524

 

How to Cite: Karnani, P., Barupa, R., Vishnoi, S.K., Choudhary, S. and Jora, R., 2022. Serum vitamin D, zinc, iron and copper levels in children with newly diagnosed coeliac disease. Sri Lanka Journal of Child Health, 51(4), pp.519–524. DOI: http://doi.org/10.4038/sljch.v51i4.10364
Published on 05 Dec 2022.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus