Start Submission Become a Reviewer

Reading: To study the clinical presentation, laboratory parameters and predictors of severity in deng...

Download

A- A+
Alt. Display

Original Articles

To study the clinical presentation, laboratory parameters and predictors of severity in dengue fever in children in a metropolitan city in India

Authors:

Sagar Karotkar,

Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi Meghe, IN
About Sagar
Assistant Professor, Department of Paediatrics
X close

Mahaveer Singh Lakra ,

Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi Meghe, IN
About Mahaveer
Senior Resident, Department of Paediatrics
X close

Ashwini Lakra,

Datta Meghe Medical College, Nagpur, IN
About Ashwini
Senior Resident
X close

Bhavana Lakhkar

Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi Meghe, IN
About Bhavana
Professor and Head, Department of Neonatology
X close

Abstract

Background: Dengue fever (DF) is an acute viral febrile illness commonly seen in India. If not identified and treated early, it may prove fatal.


Objectives: To assess the clinical presentation, laboratory parameters and predictors of severity in DF in children in a metropolitan city in India.


Method: This was a cross-sectional observational study of 100 cases of DF conducted at Jagjivan Ram Western Railway Hospital in Mumbai from June 2015 to May 2016. All inclusion and exclusion criteria were defined and patients were enrolled. Data were collected on the preformed questionnaire and analysed statistically on software.


Results: DF was commoner in males. It was equally distributed in all parts of the metropolitan city; 58% patients with DF presented without warning sign while 31% presented with warning signs. The clinical features included vomiting, abdominal pain, breathlessness, retroorbital pain, jaundice and hypotension. Fever was seen in almost 100% cases. Thrombocytopenia was the common haematological finding. Raised liver enzymes and serum bilirubin were significantly associated with DF severity. Abnormal coagulation profile was also an important finding; 16% patients had tourniquet test positive.  


Conclusions: In our study, severe abdominal pain, bleeding manifestations, breathlessness, tachycardia, tachypnoea, icterus and positive tourniquet test were significantly associated with severity. Among laboratory parameters, leucopenia (<5000/ cu mm), low platelet count, hyponatraemia, increased alanine transaminase level (>1000 IU/l), icterus and positive serology for both IgM and IgG were significantly correlated with severity.


Sri Lanka Journal of Child Health, 2022; 51(3): 404-411

How to Cite: Karotkar, S., Lakra, M.S., Lakra, A. and Lakhkar, B., 2022. To study the clinical presentation, laboratory parameters and predictors of severity in dengue fever in children in a metropolitan city in India. Sri Lanka Journal of Child Health, 51(3), pp.404–411. DOI: http://doi.org/10.4038/sljch.v51i3.10240
Published on 05 Sep 2022.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus