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Cardiac anomalies in children with non-syndromic cleft lip and palate at the Dental Teaching Hospital, Peradeniya, Sri Lanka

Authors:

Parakrama Wijekoon ,

University of Peradeniya, LK
About Parakrama
Consultant Oral & Maxillofacial Surgeon and Senior Lecturer, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences
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Sunathra Irugal Bandara,

Sirimavo Bandaranayake Specialized Children's Hospital, Peradeniya, LK
About Sunathra
Consultant Paediatric Cardiologist
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Thanuja Herath

University of Peradeniya, LK
About Thanuja
Consultant Paediatrician, Division of Pharmacology / Cleft Paediatrician and Senior Lecturer, Faculty of Dental Sciences
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Abstract

Introduction: Cardiac anomalies are the most common congenital abnormalities associated with cleft lip and/or palate, data of which, for Sri Lankan population, are not available.


Objectives: To assess the frequency of cardiac anomalies in children with non-syndromic cleft lip and/ or palate at the Dental Teaching Hospital, Peradeniya, Sri Lanka


Method: This was a retrospective cross-sectional study at the Dental Teaching Hospital, Peradeniya Sri Lanka. Records of all children aged 14 years and below with non-syndromic oral clefts, who attended the clinic between January 2018 and January 2019 were studied.


Results: Total number fulfilling inclusion criteria was 150, of which 52% were males. Cleft lip with or without cleft palate was found in 96 (64%) and 50 (33.3%) had isolated cleft palate. There were four (2.7%) with sub-mucous cleft palate. Cardiac anomalies were found in 59% comprising 17.3% with patent foramen ovale (PFO), 16.7% with ostium secundum atrial septal defect (ASD), 2% with patent ductus arteriosus (PDA), 1.3% with tetralogy of Fallot and 14.7% with other/multiple anomalies. Time gap from birth to initial echocardiography was 6 months or less in 65%. Gender or types of clefts were not significantly associated with presence of cardiac anomalies (p=0.154; p>0.05) and (p=0.377; p>0.05) respectively. Time gap from birth to initial echocardiography, and detecting cardiac anomalies was significantly associated (p= 0.027; p<0.05).


Conclusions: There was a 59% frequency of cardiac abnormalities in children with cleft lip and palate. Common cardiac anomalies detected were PFO (17.3%) and ostium secundum ASD (16.7%).


Sri Lanka Journal of Child Health, 2021; 51(1): 29-33

How to Cite: Wijekoon, P., Irugal Bandara, S. and Herath, T., 2022. Cardiac anomalies in children with non-syndromic cleft lip and palate at the Dental Teaching Hospital, Peradeniya, Sri Lanka. Sri Lanka Journal of Child Health, 51(1), pp.29–33. DOI: http://doi.org/10.4038/sljch.v51i1.9989
Published on 05 Mar 2022.
Peer Reviewed

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