Original Articles
Clinical spectrum of scrub typhus in Eastern India: A 3 year experience
Authors:
Suprit Basu,
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Suprit
Assistant Professor, Paediatrics
Sarbani Misra (Roy),
Malda Medical College, West Bengal, IN
About Sarbani
Associate Professor, Paediatrics
Tanushree Mondal,
Community Medicine, Medical College, Kolkata, LK
About Tanushree
Associate Professor
Maidul Islam ,
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Maidul
Junior Resident, Paediatrics
Sumantra Sarkar,
Diamond Harbour Medical College, Kolkata, IN
About Sumantra
Professor, Paediatrics
Mrinal Kanti Das,
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Mrinal
Professor, Paediatrics
Malay Kumar Sinha,
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Malay
Professor, Paediatrics
Sumana Datta (Kanjilal),
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Sumana
Professor, Paediatrics
Supratim Datta
Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Supratim
Professor, Paediatrics
Abstract
Introduction: Scrub typhus is a serious public health problem in Eastern India.
Objectives: To study the clinical spectrum and complications of scrub typhus and its doxycycline responsiveness.
Method: This study was carried out over a 3 year period on 203 serologically confirmed scrub typhus cases in a tertiary care centre in Eastern India.
Results: Fever (100%), facial puffiness (66.5%), vomiting (51.7%) and headache (39.4%) were common symptoms whilst hepatosplenomegaly (61.6%) and generalised lymphadenopathy (60.1%) were common signs. Meningoencephalitis (33.4%) and shock (26.6%) were common complications. Shock, congestive heart failure (CHF), disseminated intravascular coagulation (DIC), haemophagocytic lymphohistiocytosis (HLH had delayed response to doxycycline therapy.
Conclusions: In this study meningoencephalitis and shock were the common complications of scrub typhus. Meningo-encephalitis, hepatitis and pneumonia had favourable doxycycline response whilst shock, CCF. DIC, HLH and AKI had delayed doxycycline response (p<0.05).
Sri Lanka Journal of Child Health, 2021; 50(4): 610-616
How to Cite:
Basu, S., Misra (Roy), S., Mondal, T., Islam, M., Sarkar, S., Das, M.K., Sinha, M.K., Datta (Kanjilal), S. and Datta, S., 2021. Clinical spectrum of scrub typhus in Eastern India: A 3 year experience. Sri Lanka Journal of Child Health, 50(4), pp.610–616. DOI: http://doi.org/10.4038/sljch.v50i4.9847
Published on
05 Dec 2021.
Peer Reviewed
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