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Reading: Clinical spectrum of scrub typhus in Eastern India: A 3 year experience

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Original Articles

Clinical spectrum of scrub typhus in Eastern India: A 3 year experience

Authors:

Suprit Basu,

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Suprit
Assistant Professor, Paediatrics
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Sarbani Misra (Roy),

Malda Medical College, West Bengal, IN
About Sarbani
Associate Professor, Paediatrics
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Tanushree Mondal,

Community Medicine, Medical College, Kolkata, LK
About Tanushree
Associate Professor
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Maidul Islam ,

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Maidul
Junior Resident, Paediatrics
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Sumantra Sarkar,

Diamond Harbour Medical College, Kolkata, IN
About Sumantra
Professor, Paediatrics
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Mrinal Kanti Das,

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Mrinal

Professor, Paediatrics

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Malay Kumar Sinha,

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Malay
Professor, Paediatrics
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Sumana Datta (Kanjilal),

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Sumana
Professor, Paediatrics
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Supratim Datta

Institute of Postgraduate Medical Education and Research, Kolkata, IN
About Supratim
Professor, Paediatrics
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Abstract

Introduction: Scrub typhus is a serious public health problem in Eastern India.


Objectives: To study the clinical spectrum and complications of scrub typhus and its doxycycline responsiveness.


Method: This study was carried out over a 3 year period on 203 serologically confirmed scrub typhus cases in a tertiary care centre in Eastern India.


Results: Fever (100%), facial puffiness (66.5%), vomiting (51.7%) and headache (39.4%) were common symptoms whilst hepatosplenomegaly (61.6%) and generalised lymphadenopathy (60.1%) were common signs. Meningoencephalitis (33.4%) and shock (26.6%) were common complications. Shock, congestive heart failure (CHF), disseminated intravascular coagulation (DIC), haemophagocytic lymphohistiocytosis (HLH had delayed response to doxycycline therapy.


Conclusions: In this study meningoencephalitis and shock were the common complications of scrub typhus. Meningo-encephalitis, hepatitis and pneumonia had favourable doxycycline response whilst shock, CCF. DIC, HLH and AKI had delayed doxycycline response (p<0.05).


Sri Lanka Journal of Child Health, 2021; 50(4): 610-616

How to Cite: Basu, S., Misra (Roy), S., Mondal, T., Islam, M., Sarkar, S., Das, M.K., Sinha, M.K., Datta (Kanjilal), S. and Datta, S., 2021. Clinical spectrum of scrub typhus in Eastern India: A 3 year experience. Sri Lanka Journal of Child Health, 50(4), pp.610–616. DOI: http://doi.org/10.4038/sljch.v50i4.9847
Published on 05 Dec 2021.
Peer Reviewed

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