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Original Articles

Complications following ventilation therapy in newborn babies at tertiary health centre with special reference to broncho-pulmonary dysplasia

Authors:

Priyank S. Trivedi ,

Baroda Medical College, Baroda, Gujarat, IN
About Priyank

Department of Paediatrics

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Bakul Javadekar

Baroda Medical College, Baroda, Gujarat, IN
About Bakul
Department of Paediatrics
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Abstract

Background: Neonatal survival has increased after evolution of ventilation therapy in the last decade. Currently the major concerns are to prevent complications associated with ventilator therapy. 


Objectives: To do a prospective study of all ventilated newborns and assess all aspects associated with complications.


Method: Observational study was carried out at Rukmani Chainani Maternity and Neonatal Unit (Intramural Neonatal Intensive Care Unit) and Extramural Neonatal Intensive Care Unit (Em-Nicu) in Sir Sayajirao General Hospital from January to October 2019. Study was done on 224 newborns who required ventilation therapy.


Results: Of the 224 newborns, 24 (10.7%) developed broncho-pulmonary dysplasia (BPD). Average birth weights of babies with and without BPD were 2.15kg and 2.06kg respectively. Most favourable outcome was in newborns with meconium aspiration syndrome with a discharge rate of 47.9%. Next favourable outcome occurred in newborns with pneumonia requiring ventilator therapy with a discharge rate of 43.5%. There were no cases of BPD among the 24 preterm babies whose mothers were given antenatal steroids. On the other hand, among the 81 preterm babies whose mothers were not given antenatal steroids, 11 (13.6%) developed BPD. Incidence of BPD was 5.2% in newborns who required mechanical ventilation for 0-3 days, 25% in newborns who required mechanical ventilation for 4-7 days, 59% in newborns who required mechanical ventilation for 8-14 days and 83.3% in newborns who required mechanical ventilation for >14 days.


Conclusions: In our study, there was no difference in incidence of BPD in normal birth weight and low birth weight babies. The present study showed that increased duration of mechanical ventilation was associated with an increase in the incidence of complications, especially BPD. Of those requiring ventilation therapy, MAS and pneumonia had more favourable outcomes compared to hyaline membrane disease


Sri Lanka Journal of Child Health, 2021; 50(3): 478-481

How to Cite: Trivedi, P.S. and Javadekar, B., 2021. Complications following ventilation therapy in newborn babies at tertiary health centre with special reference to broncho-pulmonary dysplasia. Sri Lanka Journal of Child Health, 50(3), pp.478–481. DOI: http://doi.org/10.4038/sljch.v50i3.9729
Published on 05 Sep 2021.
Peer Reviewed

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