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Original Articles

Prevalence and pattern of dyslipidaemia among Nigerian adolescents living in Benin City: A school-based cross-sectional study

Authors:

Alphonsus N. Onyiriuka ,

University of Benin Teaching Hospital, Benin City, NG
About Alphonsus

Endocrinology and Metabolism Unit, Department of Child Health

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Nosakhare J. Iduoriyekemwen,

University of Benin Teaching Hospital, Benin City, NG
About Nosakhare
Nephrology Unit, Department of Child Health
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Wilson E. Sadoh

University of Benin Teaching Hospital, Benin City, NG
About Wilson
Cardiology Unit, Department of Child Health
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Abstract

Background: The increasing prevalence of overweight and obesity in the paediatric population can be associated with an increased rate of dyslipidaemia, a modifiable metabolic risk factor for developing cardiovascular disease.


Objectives: To estimate the prevalence and describe the pattern of dyslipidaemia among overweight/obese and normal-weight students aged 10 to 16 years, living in Benin City, Nigeria.


Method: In this case-control study, a total of 98 students (49 subjects; high BMI; ≥ 85th percentile and 49 controls; normal BMI; 5th to < 85th percentile), matched for age and gender and from similar socio-economic and ethnic background were investigated. The first public school in a list of alphabetically arranged secondary schools was selected. Thereafter, the students were randomly selected. Serum concentrations of total cholesterol, high-density lipoprotein-cholesterol (HDL-C), triglycerides and low-density lipoprotein-cholesterol were determined, using an automated analyzer with commercially available kits.


Results:Of the 98 students who were investigated, there was at least one “abnormal” lipid concentration in 31 (63.3%; 95% Confidence interval, CI=49.8-76.8) adolescents with overweight/obese and the corresponding prevalence of 51.0% (95% CI=43.9-58.1) in adolescents with normal BMI; p-value >0.05. Among overweight/obese participants, the prevalence of dyslipidaemia was significantly higher in girls than boys, p < 0.05. The frequency of borderline-low HDL-C in overweight/obese and normal-BMI participants was 18.4% and 16.3%, respectively. In both overweight/obese and normal-BMI participants, the most common type of dyslipidaemia was low HDL-C with a prevalence of 62.3% (95% CI= 55.6-69.2) and 51.0% (95% CI=43.9-58.1) in overweight/obese and normal-BMI participants, respectively; p >0.05.


Conclusions: A high proportion of adolescents with either overweight/obesity or normal BMI had dyslipidaemia with the former having a higher proportion. Low HDL-C level was the most common abnormality in dyslipidaemia.

 

Sri Lanka Journal of Child Health, 2021; 50(3): 385-392

How to Cite: Onyiriuka, A.N., Iduoriyekemwen, N.J. and Sadoh, W.E., 2021. Prevalence and pattern of dyslipidaemia among Nigerian adolescents living in Benin City: A school-based cross-sectional study. Sri Lanka Journal of Child Health, 50(3), pp.385–392. DOI: http://doi.org/10.4038/sljch.v50i3.9685
Published on 05 Sep 2021.
Peer Reviewed

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