Original Articles
Clinical profile and laboratory findings of patients with thrombocytopenia in hospital set up: A hospital based prospective study
Authors:
Priyanka Agarwal ,
Institute of Medical Sciences and SUM Hospital, IN
Dillip Kumar Dash,
Institute of Medical Sciences and SUM Hospital, IN
Mrinal Sinha,
Institute of Medical Sciences and SUM Hospital, IN
Mamta Kumari,
Institute of Medical Sciences and SUM Hospital, IN
Mamta Devi Mohanty,
Institute of Medical Sciences and SUM Hospital
A S A M Srikant
Institute of Medical Sciences and SUM Hospital, IN
Abstract
Introduction: Thrombocytopenia is commonly encountered in our routine clinical practice. Causes being numerous, it poses a challenge in evaluating and treating the patients.
Objectives: To determine the causes, clinical profile and outcome of thrombocytopenia in children aged 1 month to 14 years who were admitted in our set up.
Method: This was a prospective study done on 200 patients aged 1 month to 14 years with thrombocytopenia admitted to the Institute of Medical Sciences AND SUM Hospital, Bhubaneshwar, Odisha, India with various complaints, from 01-08-2017 TO 01-08-2019.
Results: Fifty six (28%) children were in the 3-6 year age group. In 116 (58 %) children the thrombocytopenia was in the rainy season. Common causes of thrombocytopenia were dengue (18.5%), sepsis (16.5%) and scrub typhus (16%). Petechiae was the commonest bleeding manifestation (62%) followed by epistaxis (13.7%). Out of 32 cases of scrub typhus 23 (71.8%) had deranged liver function tests. Out of the 8 children that died, one had platelet count ≤10,000/µL, one had platelet count 10,000-20,000/µL while 3 each had platelet counts in the range of 22,000 – 50,000/µL and >50,000/µL respectively
Conclusions: There was male predominance. The commonest age group was 3-6 years. Thrombocytopenia was more common during the rainy season. Common causes were dengue, septicaemia and scrub typhus. Common clinical presentations were fever, organomegaly, generalised myalgia, lymphadenopathy and headache. Petechiae/Purpura was the most common bleeding manifestation. Mortality rate was 4%.
Sri Lanka Journal of Child Health, 2021; 50(1): 94-102
How to Cite:
Agarwal, P., Dash, D.K., Sinha, M., Kumari, M., Mohanty, M.D. and Srikant, A.S.A.M., 2021. Clinical profile and laboratory findings of patients with thrombocytopenia in hospital set up: A hospital based prospective study. Sri Lanka Journal of Child Health, 50(1), pp.94–102. DOI: http://doi.org/10.4038/sljch.v50i1.9409
Published on
05 Mar 2021.
Peer Reviewed
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