Original Articles
Correlation of peak expiratory flow rate with anthropometric parameters in apparently healthy children with sickle cell anaemia in Lagos
Authors:
Olufemi Samuel Akodu ,
Olabisi Onabanjo University Teaching Hospital, Nigeria,, NG
About Olufemi
Olabisi Onabanjo University Teaching Hospital, Nigeria,
Oluseyi Abiodun Faleti,
Mercy Street Children Hospital, Nigeria, NG
About Oluseyi
Mercy Street Children Hospital, Nigeria
Abiodun Folashade Adekanmbi,
Olabisi Onabanjo University Teaching Hospital, Nigeria, NG
About Abiodun
Olabisi Onabanjo University Teaching Hospital, Nigeria
Tinuade Adetutu Ogunlesi
Olabisi Onabanjo University Teaching Hospital, Nigeria, NG
About Tinuade
Olabisi Onabanjo University Teaching Hospital, Nigeria
Abstract
Background: Abnormalities of pulmonary function frequently occur in children with sickle cell anaemia (SCA) but data demonstrating correlation of anthropometric parameters with peak expiratory flow rate (PEFR) are scanty. The mini Wright peak flow meter is easy available, relatively affordable, and portable making it a useful device for determining the pulmonary functions in resource-limited settings.
Objectives: To determine the correlation between PEFR with age and anthropometric parameters in apparently healthy children with SCA.
Method: PEFR was measured using a mini Wright peak flow meter in 200 children, 100 children with SCA and 100 healthy controls. Correlation of PEFR with age, height, weight, and chest circumference was calculated.
Results: Mean PEFR was significantly less in children with Hb SS genotype than in children with Hb AA genotype, irrespective of gender. Mean PEFR increased with age irrespective of gender or haemoglobin genotype. Examination on Pearson correlation coefficient showed significant positive correlation between age, sitting height, standing height, weight, body mass index (BMI), arm span and PEFR in subjects with SCA and controls. However, BMI had significant correlation in both subjects and controls but weaker than other variables.
Conclusions: PEFR correlates more with age, sitting height, standing height, weight and arm span. Thus, the age and body size, but not the body fat of the child is important in determining the final responses of lung function in children with SCA.
Sri Lanka Journal of Child Health, 2020; 49(4): 329-334
How to Cite:
Akodu, O.S., Faleti, O.A., Adekanmbi, A.F. and Ogunlesi, T.A., 2020. Correlation of peak expiratory flow rate with anthropometric parameters in apparently healthy children with sickle cell anaemia in Lagos. Sri Lanka Journal of Child Health, 49(4), pp.329–334. DOI: http://doi.org/10.4038/sljch.v49i4.9263
Published on
05 Dec 2020.
Peer Reviewed
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