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A retrospective study of haemophagocytic lymphohistiocytosis in children in a tertiary care hospital in Eastern India

Authors:

Suparna Guha ,

Vivekananda Institute of Medical Sciences, Kolkata India, IN
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Vivekananda Institute of Medical Sciences, Kolkata India
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Gautam Guha

Nil Ratan Sircar Medical College and Hospital, India, LK
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Nil Ratan Sircar Medical College and Hospital, India

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Abstract

Introduction: Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder that is being increasingly reported in children from the Indian subcontinent.

Objective: To describe the profile of HLH in children in a tertiary care hospital in Eastern India.

Method: This is a retrospective study of all children diagnosed to have HLH from March 2015 to August 2016 and admitted to the paediatric department of Vivekananda Institute of Medical Sciences, India. The case records of the children with HLH were analysed.

Results: Fifteen children were diagnosed with HLH during the study period. All were secondary cases, infection being the predominant cause. More than 50% needed some immune modulation in the form of steroids /intravenous immunoglobulin. Two succumbed to complications.

Conclusions: All 15 cases of HLH were secondary (acquired). Eighty percent of the cases were secondary to infection.

Sri Lanka Journal of Child Health, 2018; 47: 219-222

How to Cite: Guha, S. & Guha, G., (2018). A retrospective study of haemophagocytic lymphohistiocytosis in children in a tertiary care hospital in Eastern India. Sri Lanka Journal of Child Health. 47(3), pp.219–222. DOI: http://doi.org/10.4038/sljch.v47i3.8542
Published on 05 Sep 2018.
Peer Reviewed

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