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Reading: Blood lactate as a predictor of mortality in critically ill children

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Blood lactate as a predictor of mortality in critically ill children

Authors:

Channanayaka Chandrashekar ,

JSS University, JSS Medical College, Mysore, India, IN
About Channanayaka

JSS University, JSS Medical College, Mysore, India

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Monisha Prabhakar,

JSS University, JSS Medical College, Mysore, India, IN
About Monisha
JSS University, JSS Medical College, Mysore, India
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M Santhoshkumar,

JSS University, JSS Medical College, Mysore, India, IN
About M
JSS University, JSS Medical College, Mysore, India
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Reddy K Harish

JSS University, JSS Medical College, Mysore, India, IN
About Reddy
JSS University, JSS Medical College, Mysore, India
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Abstract

Objective: To study blood lactate levels at admission in predicting mortality in critically ill children requiring haemodynamic / respiratory support.

Method: A prospective observational study was done in 200 critically ill admissions to the paediatric intensive care unit (PICU), requiring haemodynamic / respiratory support. The demographic data, clinical status, organ involvement and therapeutic interventions were recorded in a predesigned proforma until hospital discharge or death. Lactate levels were estimated at admission and were correlated with the mortality and organ dysfunction 

Results: The geometric mean of lactate levels at admission in survivors and non survivors were 20.58 mg/dl and 50.48 mg/dl respectively. Blood lactate was 82.9% sensitive and 85.4% specific at the optimal cut-off value of 33.7 mg/dl. The positive likelihood ratio was 5.67 and the negative likelihood ratio 0.2.

Conclusions: Blood lactate levels at admission predict mortality in critically ill children requiring haemodynamic/respiratory support.

Sri Lanka Journal of Child Health, 2018; 47(1): 40-43

How to Cite: Chandrashekar, C. et al., (2018). Blood lactate as a predictor of mortality in critically ill children. Sri Lanka Journal of Child Health. 47(1), pp.40–43. DOI: http://doi.org/10.4038/sljch.v47i1.8428
Published on 05 Mar 2018.
Peer Reviewed

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