Start Submission Become a Reviewer

Reading: Platelet profile and its correlation to paediatric patients with acute malaria in a tertiary...

Download

A- A+
Alt. Display

Original Articles

Platelet profile and its correlation to paediatric patients with acute malaria in a tertiary care hospital

Authors:

Gurudutt Joshi ,

Department of Paediatrics, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India, IN
About Gurudutt

Associate Professor, Department of Paediatrics, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India

X close

Deepak Gamit

Department of Paediatrics, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India, IN
About Deepak
Medical Officer, Department of Paediatrics, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India
X close

Abstract

Introduction: Few studies are available as regards status of platelets in malaria in paediatric patients.

 Objectives: To correlate factors such as age, type of malaria species and degree of parasitaemia with the degree of thrombocytopenia and to correlate the mean platelet volume and platelet distribution width with the malaria species.

 Method: A prospective observational study was conducted on patients 1 to 17 years of age admitted to the department of paediatrics of a tertiary level hospital from January 2014 to November 2014 with a history of acute fever (less than 5 days) and peripheral blood smear positive for malarial parasites with the rapid diagnostic test. A detailed history and examination of the patients along with the demographic profile was entered in the predesigned proforma. Automated Coulter haematology analyser (Abacus) was used for investigations. The data was analysed by SPSS 16 statistical analysis. Comparison among three groups of continuous data was done using a One-way ANOVA, whereas data not conforming to normal distribution were compared by a Kruskal-Wallis Test. Categorical data were compared using Pearson Chi-Square Test.

 Results:There were 105 patients who met the inclusion criteria. Of them, 60% had vivax malaria, 33% had falciparum malaria and the rest had mixed malaria. Thrombocytopenia was present in 85%, severe thrombocytopenia (<50,000/cu mm) being present in 36%. The platelet count significantly correlated with the type of malaria and the degree of parasitaemia. The platelet count decreased as the age increased in moderate to severe thrombocytopenia. There was also correlation between the mean platelet volume but not the platelet distribution width and the malaria species.

Conclusion: Thrombocytopenia was present in 85% of patients, the degree of thrombocytopenia correlating significantly with the degree of parasitaemia and the type of malaria. The MPV but not the PDW correlated significantly with the type of malaria species.

(Key words: Malaria, thrombocytopenia, rapid diagnostic test, mean platelet volume, platelet distribution width).

Sri Lanka Journal of Child Health, 2016; 45(2):107-110

DOI: http://dx.doi.org/10.4038/sljch.v45i2.8117                    

How to Cite: Joshi, G. and Gamit, D., 2016. Platelet profile and its correlation to paediatric patients with acute malaria in a tertiary care hospital. Sri Lanka Journal of Child Health, 45(2), pp.107–110. DOI: http://doi.org/10.4038/sljch.v45i2.8117
Published on 06 Jun 2016.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus