Start Submission Become a Reviewer

Reading: Clinico-pathological correlations of childhood glomerular disease in Eastern India

Download

A- A+
Alt. Display

Original Articles

Clinico-pathological correlations of childhood glomerular disease in Eastern India

Authors:

Pawan Pradeep Mutalik ,

Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India, IN
About Pawan
Post Graduate, Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India

 

X close

Subal Kumar Pradhan,

Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India, IN
About Subal
Assistant Professor, Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India
X close

Bikrant Kumar Prusty,

Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India, IN
About Bikrant
Postgraduate,Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India
X close

Kedar Das,

Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India, IN
About Kedar
Associate Professor, Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India
X close

Saroj Kumar Satapathy

Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India, IN
About Saroj
Professor, Department of Paediatrics, SVPPGIP & SCB Medical College, Utkal University, India
X close

Abstract

Background: Histopathological examination of renal biopsy has an important role in establishing glomerular disease in children.

Objective: To describe and correlate the types of glomerular diseases reported in native kidney biopsy and their clinical presentations.

Method: This retrospective and descriptive study was conducted from December 2009 to December 2013 at the Department of Paediatrics, SVPPGIP & SCB Medical College, Cuttack, Odisha, India. A total of 142 renal biopsies were performed in 140 children aged 6 months to 14 years. Their demographic data, indication for renal biopsy and histological diagnosis were analysed and correlated with clinical presentations in the study.

Results: In 136 (97.1%) of 140 children, the renal histopathology revealed glomerular diseases. The male to female ratio was 1.5:1. The most frequent types of biopsy-proven renal diseases were: Minimal Change Disease 47 (33.5%), Focal Segmental Glomerulosclerosis 29 (20.7%), IgA nephropathy 21 (15%), Lupus nephritis 11 (7.8%) and Post-streptococcal glomerulonephritis 8 (5.7%). Nephrotic syndrome was the most common glomerular disease 106 (77.9%).

Conclusions: In our study, Minimal Change Disease was the most common biopsy proven glomerular disease and nephrotic syndrome was the most frequent clinical presentation. The best clinico-pathological correlation was seen with lupus nephritis cases.

Sri Lanka Journal of Child Health, 2015; 44(1): 31-37

DOI: http://dx.doi.org/10.4038/sljch.v44i1.7960

How to Cite: Mutalik, P.P., Pradhan, S.K., Prusty, B.K., Das, K. and Satapathy, S.K., 2015. Clinico-pathological correlations of childhood glomerular disease in Eastern India. Sri Lanka Journal of Child Health, 44(1), pp.31–37. DOI: http://doi.org/10.4038/sljch.v44i1.7960
Published on 08 Mar 2015.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus